N-methyl-d-aspartate receptor antibody-related pathologies and pre-existent mental state disorders

We read with interest the article by Mantere and colleagues, who tested serum autoantibodies against a wide spectrum of neuronal antigens in a large series of patients with a first-episode psychosis, or clinical high-risk (CHR) for psychosis (Mantere et al., 2018). They found that only one patient with a history of recurrent major depressive episodes was seropositive for antibodies to the N-methyl-d-aspartate receptor (NMDAR). The patient was referred to the study for symptoms of CHR for psychosis.

Source: Schizophrenia Research - July 2, 2018 Category: Psychiatry Authors: Federico Massa, Diego Franciotta, Matteo Gastaldi, Giovanni Luigi Mancardi, Luana Benedetti Tags: Letter to the editor Source Type: research