The Influence of LPS-Induced Maternal Inflammation on Postnatal Collagen-Induced Arthritis

In conclusion, maternal inflammation does not merely suppress inflammation; it may delay CIA in offspring. The analysis of inflammatory cytokines and leptin concentrations at 26 weeks suggests that the pathophysiology of arthritis was worsening. This study also suggests that maternal inflammation modulates postnatal inflammatory response patte rns in offspring.
Source: Inflammation - Category: Allergy & Immunology Source Type: research