Lamellar hole-associated epiretinal proliferation in lamellar macular hole and full-thickness macular hole in high myopia

Conclusion: Lamellar hole-associated epiretinal proliferation in HM tended to be more widespread and adherent to the posterior hyaloid than in eyes without HM. Visual outcomes after LMH repair in eyes with LHEP and HM are less favorable than eyes with LHEP and without HM, but similar to eyes with HM and without LHEP.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research

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CONCLUSION: hAM transplantation is a novel technique in case of retinal detachment recurrences to seal retinal holes over high myopic chorioretinal atrophy. The adjunctive use of PRP and high viscosity silicon oil allows to reducing the standard face-down positioning timing, representing a valid solution for elderly patients who have difficulties maintaining the position for long periods. PMID: 32878471 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
Rhegmatogenous retinal detachment (RRD) happens when a vitreous humor –filled gap forms between the neurosensory and the retinal pigment epithelium layers. Although the condition is relatively infrequent and has surgical repair success rates greater than 80%, the visual acuity outcomes are poor in half of cases, especially patients who present with a detached macula . Male sex, myopia, and cataract surgery are all risk factors disproportionally overrepresented among patients with RRD. Because of the difficulty assembling sufficiently well-powered prospective studies, which is particularly intense for low-frequency di...
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research
Purpose: To identify factors associated with persistent subretinal fluid (SRF) after small-gauge pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: This retrospective study included patients from 2 tertiary centers who underwent pars plana vitrectomy for repair of rhegmatogenous retinal detachment between 2013 and 2016. Preoperative and intraoperative parameters were examined for association with development of SRF. Results: Overall, 153 eyes of 153 patients, mean age of 55.2 ± 17.9 years were included. Persistent SRF occurred in 15.0% (n = 23) and was associated with high myopia (65.22 vs. 26.15%, P
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
First patients begin promising gene therapy Related items fromOnMedica Gene therapy hopes for AMD Baby born with three-person DNA Myopia could be linked to longer periods spent in education Mexican fish offer clues on heart repair Online resource aims to help GPs spot early signs of degenerative muscle disease
Source: OnMedica Latest News - Category: UK Health Source Type: news
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: Cigarette smoking and macular involvement are significant risk factors predictive of PVR formation after uncomplicated primary retinal detachment repair.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
This study examined visual and anatomical outcomes of pediatric RD undergoing surgical repair at a single university referral center. Methods: A retrospective consecutive case series of patients clinically diagnosed and undergoing surgery for RD between birth and 15 years of age from 2002 to 2013 at a single academic institution. Results: A total of 206 patients (231 eyes) were included in this study, of which 25 (12%) had bilateral RD. Of those patients, 67 (29%) had TRD (retinopathy of prematurity, persistent fetal vasculature, or familial exudative vitreoretinopathy), 51 (22%) had rhegmatogenous retinal detachment...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
CONCLUSIONS: A distinctive optic nerve head dysgenesis is part of Donnai-Barrow syndrome and can help distinguish its ocular phenotype from other vitreo-retinopathies associated with high myopia. PMID: 29388841 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Publication date: Available online 28 June 2017 Source:Progress in Retinal and Eye Research Author(s): C. Ellis Wisely, Javed A. Sayed, Heather Tamez, Chris Zelinka, Mohamed H. Abdel-Rahman, Andy J. Fischer, Colleen M. Cebulla The domestic chicken, Gallus gallus, serves as an excellent model for the study of a wide range of ocular diseases and conditions. The purpose of this manuscript is to outline some anatomic, physiologic, and genetic features of this organism as a robust animal model for vision research, particularly for modeling human retinal disease. Advantages include a sequenced genome, a large eye, relative ease...
Source: Progress in Retinal and Eye Research - Category: Opthalmology Source Type: research
Publication date: Available online 31 March 2017 Source:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Author(s): Olivier Cases, Antoine Obry, Sirine Ben-Yacoub, Sébastien Augustin, Antoine Joseph, Géraldine Toutirais, Manuel Simonutti, Annabel Christ, Pascal Cosette, Renata Kozyraki High myopia (HM) is one of the main causes of visual impairment and blindness all over the world and an unsolved medical problem. Persons with HM are predisposed to other eye pathologies such as retinal detachment, myopic retinopathy or glaucomatous optic neuropathy, complications that may at least partly resul...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
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