Impact of Heart Rate Reduction with Maximal Tolerable Dose of Bisoprolol on Left Ventricular Reverse Remodeling.

Conclusion: High baseline HR (≥ 75 bpm) showed an association with LVRR and improvement of NT-proBNP and GAS in patients with HFrEF. This seems to be due to a large HR reduction after treatments with bisoprolol. Trial registry at www.ClinicalTrials.gov, NCT00749034. PMID: 29915522 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29915522?dopt=Abstract

Source: J Korean Med Sci - June 18, 2018 Category: General Medicine Authors: Choi SW, Han S, Shim WJ, Choi DJ, Kim YJ, Yoo BS, Hwang KK, Jeon HK, Shin MS, Ryu KH Tags: J Korean Med Sci Source Type: research