Limb-bud and Heart Overexpression Inhibits the Proliferation and Migration of PC3M Cells

Conclusions: Our results reveal that LBH expression is down-regulated in the tissue and cell lines of PCa. LBH overexpression inhibits PC3M cell proliferation and tumor growth by inducing cell cycle arrest through down-regulating cyclin D1and cyclin E2 expression. LBH might be a therapeutic target and potential diagnostic marker in PCa.

Source: Journal of Cancer - June 20, 2018 Category: Cancer & Oncology Authors: Qicai Liu, Ermao Li, Long Huang, Minsheng Cheng, Li Li Tags: Research Paper Source Type: research