The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma

Conclusion: NPC1L1 and NPC2 were lowly expressed in HCC compared with peritumoral liver tissues, and low expression of NPC1L1 and NPC2 in HCC tissues may indicate poor outcome of HCC patients after surgery. NPC1L1/NPC2 combination is an independent prognostic factor for OS and TTR in postoperative HCC patients.

Source: Journal of Cancer - June 20, 2018 Category: Cancer & Oncology Authors: Ke-Ji Chen, Ri-Ming Jin, Chun-Chao Shi, Rui-Liang Ge, Lei Hu, Qi-Fei Zou, Quan-Yu Cai, Guang-Zhi Jin, Kui Wang Tags: Research Paper Source Type: research