HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling

Conclusions: Overall, future treatments through activating Tid1 expression or inversely repressing the oncogenic function of Galectin-7 may exhibit great potential in targeting HNSCC progression.

Source: Theranostics - June 20, 2018 Category: Molecular Biology Authors: Yu-Syuan Chen, Ching-Wen Chang, Yeou-Guang Tsay, Liu-Ying Huang, Yi-Chen Wu, Li-Hao Cheng, Cheng-Chieh Yang, Cheng-Hsien Wu, Wan-Huai Teo, Kai-Feng Hung, Chih-Yang Huang, Te-Chang Lee, Jeng-Fan Lo Tags: Research Paper Source Type: research