Non-Small Cell Lung Cancer Transdifferentiation into Small Cell Lung Cancer: A Case Series

Lung cancer is considered one of the leading causes of death due to cancer worldwide [1]. The classification of lung cancer is based on histologic characteristics, and it is mainly divided into two subtypes: non-small cell lung cancer (NSCLC), which is responsible for 85% of lung cancer cases, and small cell lung cancer (SCLC) [1]. NSCLC is further subdivided into adenocarcinoma, squamous cell carcinoma, and large cell carcinoma [1,2]. Although most lung cancers are classified as either NSCLC or SCLC and probably remain as such, the development of safer biopsy methods has allowed more frequent repeat biopsies, which sometimes reveal changing histologic characteristics.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research