Female sex as a biological variable: A review on younger patients with acute coronary syndrome

Although acute coronary syndrome (ACS) mainly occurs in individuals>60 years, younger adults can be affected as well. Women continue to be at higher risk of 30-day mortality after ST-segment elevation myocardial infarction (STEMI) even in the current era of percutaneous coronary intervention (PCI). Importantly, the excess mortality among women is only significant at younger ages. Previous work has suggested that the reason for the differences in outcome is likely multifactorial and may partially be explained by some of the following factors: atypical presentation, delayed presentation, under recognition of STEMI at initial medical contact, and underuse of medications because of concern regarding increased risk of bleeding.
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research