Vestibular Function and Hippocampal Volume in the Baltimore Longitudinal Study of Aging (BLSA)

Conclusions: Lower cVEMP amplitude (i.e., reduced saccular function) was significantly associated with lower mean hippocampal volume. This is in line with previous work demonstrating a link between saccular function and spatial cognition. Hippocampal atrophy may be a mechanism by which vestibular loss contributes to impaired spatial cognition in older adults. Future work using longitudinal data will be needed to evaluate the causal nature of the association between vestibular loss and hippocampal atrophy.
Source: Otology and Neurotology - Category: ENT & OMF Tags: Vestibular Disorders Source Type: research