900p * prognostic significance of serum alphafoetoprotein early decline in ovarian yolk sac tumor

Conclusions: Serum AFP early decline help to identify poor prognosis ovarian YSTs pts. This may be relevant for the management of OYSTs since it has been shown in a phase III study (GETUG 13) in testicular poor prognosis germ cell tumor that early switch to a dose dense chemotherapy regimen for pts with slow tumor marker decline reduces the risk of progression or death.Disclosure: All authors have declared no conflicts of interest.

Source: Annals of Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Rouge, T. D. L. M., Pautier, P., Duvillard, P., Rey, A., Morice, P., Meder, C. H., Kerbrat, P., Culine, S., Fizazi, K., Lhomme, C. Tags: gynaecological cancers Source Type: research