Dysregulation of microRNA ‑23b‑3p contributes to the development of intracranial aneurysms by targeting phosphatase and tensin homolog.

In conclusion, PTEN was found to be a virtual target of miR‑23b‑3p, and a negative regulatory association existed between miR‑23b‑3p and PTEN. miR‑23b‑3p and PTEN interfered with the viability and apoptosis of SMCs.
PMID: 29845190 [PubMed - as supplied by publisher]

Source: International Journal of Molecular Medicine - May 25, 2018 Category: Molecular Biology Authors: Guo D, Wang YW, Yan L, Ma J, Han XW, Shui SF Tags: Int J Mol Med Source Type: research