Treatment intensification with autologous stem-cell transplantation and lenalidomide maintenance improves survival outcomes of newly diagnosed multiple myeloma patients in complete response

In CR patients, HDT-ASCT consolidation improved PFS, PFS2 and OS vs R-Alk consolidation, and R- maintenance also enhanced PFS vs no maintenance. The survival advantage with HDT-ASCT over R-Alk in CR patients may be attributed to a higher MRD negativity rate induced by HDT-ASCT.

Source: Clinical Lymphoma, Myeloma and Leukemia - May 28, 2018 Category: Hematology Authors: Roberto Mina, Maria Teresa Petrucci, Paolo Corradini, Stefano Spada, Francesca Patriarca, Chiara Cerrato, Lorenzo De Paoli, Norbert Pescosta, Roberto Ria, Alessandra Malfitano, Pellegrino Musto, Luca Baldini, Tommasina Guglielmelli, Barbara Gamberi, Donat Tags: Original Study Source Type: research