A New Study Links Antidepressants to Weight Gain

A new study published in The BMJ has found that antidepressant use may be associated with weight gain over time. “Patients who were normal weight were more likely to transition to overweight, and overweight patients were more likely to transition to obesity if they were treated with antidepressants,” said study co-author Rafael Gafoor, a primary care and public health researcher at King’s College London, in an email to TIME. The researchers used data from the UK Clinical Practice Research Datalink, a large collection of electronic health records. Their analysis included almost 295,000 people of all different weights. Researchers then monitored the health records for antidepressant use and weight gain over time, accounting for other factors that could affect weight gain, like age, chronic disease diagnoses, smoking status and taking other drugs. Those who were prescribed antidepressants during the first year of the study were 21% more likely to have gained at least 5% of their starting body weight over the 10 years of follow-up, compared to people not taking the drugs. The risk of weight gain appeared to be greatest in the second and third years of treatment and remained elevated for six years after beginning a course of treatment. “[It] may take some time for weight gain to be noticeable and recorded into medical records,” Gafoor says. Some drugs were more strongly associated with weight gain than others, the study found. People taking mirtazap...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Mental Health/Psychology onetime Source Type: news

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Publication date: Available online 25 June 2019Source: Social Science &MedicineAuthor(s): Claire L. Niedzwiedz, Katie H. Thomson, Clare Bambra, Jamie R. PearceAbstractStudies from single countries suggest that local labour market conditions, including rates of employment, tend to be associated with the health of the populations residing in those areas, even after adjustment for individual characteristics including employment status. The aim of this study is to strengthen the cross-national evidence base on the influence of regional employment levels and individual worklessness on health during the period of the Great R...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Background: Falls and fall risk factors are common among people living with HIV (PLWH). We sought to identify fall risk factors among men with and without HIV. Methods: Men aged 50–75 years with (n = 279) and without HIV (n = 379) from the Bone Strength Substudy of the Multicenter AIDS Cohort Study were included. Multinomial logistic regression models identified risk factors associated with falling. Results: One hundred fourteen (41%) PLWH and 149 (39%) of uninfected men had ≥1 fall; 54 (20%) PLWH and 66 (17%) of uninfected men experienced ≥2 falls over 2 years. Five and 3% of PLWH and uninfected men, r...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
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Source: Nutritional Neuroscience - Category: Nutrition Authors: Source Type: research
AbstractSettingEtiopathogenic factors of physical disability in obesity are numerous, underestimated and not sought in the non-geriatric population. Amongst these factors, depression may favor the development of sarcopenic obesity by reducing strength and physical performance even in the absence of overt muscle loss.Objectives&participantsTo study the link between depression status and muscle functional disorders (dynapenia) in a population of adult subjects with severe and morbid obesity.MeasurementsPatients were assessed for body composition, grip strength, the Short Physical Performances Battery test (SPPB), for dep...
Source: The Journal of Nutrition, Health and Aging - Category: Nutrition Source Type: research
This study sought to investigate what could be learned from how these men have fared. The men were born in 1925-1928 and similar health-related data from questionnaires, physical examination, and blood samples are available for all surveys. Survival curves over various variable strata were applied to evaluate the impact of individual risk factors and combinations of risk factors on all-cause deaths. At the end of 2018, 118 (16.0%) of the men had reached 90 years of age. Smoking in 1974 was the strongest single risk factor associated with survival, with observed percentages of men reaching 90 years being 26.3, 25.7, ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Brugnera A, Carlucci S, Compare A, Tasca GA Abstract Interpersonal problems play a prominent role in the development of binge-eating disorder (BED), so that reducing their intensity may be a key focus of many psychological interventions. In recent years, several interpersonal treatments for BED were developed, which posit that binge-eating arises to manage relational problems. However, few studies have evaluated the prototypical interpersonal problems, and no studies evaluated the longitudinal changes in interpersonal functioning after treatment within this population. We investigated the severity and prot...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
In this study, compared to young mice (4 months of age), aged mice (20-22 months of age) exhibited increased left ventricular weight and cardiomyocyte volume, and showed reduction in cardiomyocyte number, together with reduced ventricular function, indicating the pathological roles of cardiomyocyte senescence in the aged heart. Heart failure can be characterized into two types depending on the level of systolic function. One is described as heart failure with reduced ejection fraction (HFrEF), another is classified as heart failure with preserved ejection fraction (HFpEF), and both types of heart failure are prevale...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
By Christian Jarrett There is increasing recognition that while our personality traits are stable enough to shape our lives profoundly, they are also partly malleable, so that our choices and experiences can feedback and influence the kind of people we become. A new study in the Journal of Research in Personality shines a light on a highly consequential behaviour that captures this dynamic – smoking cigarettes. The results add “… to existing knowledge on the implications of smoking by showing that this behaviour is also likely to alter individuals’ characteristic ways of thinking, feeling, and beha...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Health Personality Source Type: blogs
Authors: Bolton L Abstract Many patients with end-stage kidney disease prefer peritoneal dialysis (PD) to hemodialysis to replace kidney function1 but avoid PD due to fears of serious complications, such as peritonitis or catheter exit site and tunnel infections, which often have higher incidences than those recommended by the International Society for Peritoneal Dialysis (ISPD). Factors that increase the risk of PD-related peritonitis include patient nasal Staphylococcus aureus carriage, diabetes, advanced age, obesity, depression, cardiovascular disease, and catheter connection methods or exit site infection (ESI...
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
This study explored the association between obesity and polypharmacy among AA older adults who were residing in poor urban areas of South Los Angeles. We also investigated role of gender as the moderator and multimorbidity as the mediator of this association. In a community-based study in South Los Angeles, 308 AA older adults (age ≥ 55 years) were entered into this study. From this number, 112 (36.4%) were AA men and 196 (63.6%) were AA women. Polypharmacy (taking 5+ medications) was the dependent variable, obesity was the independent variable, gender was the moderator, and multimorbidity (number of chronic medical...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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