Impact of Female Sex on Clinical Outcomes in the FIRE AND ICE Trial of Catheter Ablation for Atrial Fibrillation [Original Articles]

Conclusions:
After catheter ablation of paroxysmal AF, female sex was associated with an almost 40% increase in the risks of primary efficacy failure and cardiovascular rehospitalization. Primary efficacy failure was also adversely impacted by a history of direct current cardioversion, whereas hypertension had a negative impact on cardiovascular rehospitalization. History of AF was the only predictor of repeat ablation.

Clinical Trial Registration:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT01490814.

Source: Circulation: Arrhythmia and Electrophysiology - April 26, 2018 Category: Cardiology Authors: Kuck, K.-H., Brugada, J., Furnkranz, A., Chun, K. R. J., Metzner, A., Ouyang, F., Schluter, M., Elvan, A., Braegelmann, K. M., Kueffer, F. J., Arentz, T., Albenque, J.-P., Kuhne, M., Sticherling, C., Tondo, C., on behalf of the FIRE AND ICE Investigators Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Original Articles Source Type: research