Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate.

CONCLUSION: This study shows that efflux activity contributes to colistin heteroresistance in an MDR A. baumannii clinical isolate. The use of efflux inhibitors as adjuvants of the therapy can resensitize A. baumannii to colistin and prevent the emergence of drug resistance. PMID: 29717972 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29717972?dopt=Abstract

Source: Journal of Medical Microbiology - May 2, 2018 Category: Microbiology Authors: Machado D, Antunes J, Simões A, Perdigão J, Couto I, McCusker M, Martins M, Portugal I, Pacheco T, Batista J, Toscano C, Viveiros M Tags: J Med Microbiol Source Type: research