Cortical modulation of brainstem circuits is abnormal in cervical dystonia

Discussion Enhancement of hand-evoked BR is a normal phenomenon that provides evidence for top-down modulation of its neural circuitry. In cervical dystonia, the normal modulation is lost which suggests abnormal modulatory effect of higher-order centers upon brainstem circuits. The pattern of alteration also differs if there is no sensory trick.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research