All in the Family: Repeats and ALS/FTD.

All in the Family: Repeats and ALS/FTD. Trends Neurosci. 2018 May;41(5):247-250 Authors: Pattamatta A, Cleary JD, Ranum LPW Abstract In 2011, an intronic (G4C2)•(G2C4) expansion was shown to cause the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This discovery linked ALS with a clinically distinct form of dementia and a larger group of microsatellite repeat diseases, and catalyzed basic and translational research. PMID: 29703376 [PubMed - in process]
Source: Trends in Neurosciences - Category: Neuroscience Authors: Tags: Trends Neurosci Source Type: research