GSE104050 NUPR1 depletion activates premature senescence and overcomes tamoxifen resistance in breast cancer cells

ConclusionsCollectively, these findings suggest a critical role for NUPR1 as a transcriptional regulator that enables the drug persistence of breast cancers, thus providing a susceptible target to diagnose and treat drug resistance.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research