Medical News Today: What causes a chronic cough?

A chronic cough is one that lasts for 8 weeks in adults or 4 weeks in children. It may produce mucus or be dry and tickle the throat. Common causes of a persistent cough include asthma and bronchitis. Less commonly, it can indicate lung cancer or heart problems. Learn more about causes, symptoms, and treatments here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

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We report the case of a 53 year-old male presenting with hematuria, pain and induration of the penis 2 and half years after the diagnosis of left colon cancer. CT scan demonstrated involvement of the corpus spongiosum and corpora cavernosa with enlarged external inguinal lymph nodes and asymptomatic metastasis in the liver and lungs.The finding of a penile lesion in a cancer patient is an alarming sign and should indicate a disseminated disease. The prognosis of penile metastasis is poor.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
Publication date: Available online 16 March 2019Source: Preventive MedicineAuthor(s): Xuanzi Qin, Rebekah H. Nagler, Erika Franklin Fowler, Sarah E. GollustAbstractThe American Cancer Society and the U.S. Preventive Task Force recently recommended that women initiate routine breast cancer screening at older ages (45 and 50, respectively) than previously recommended, and both organizations emphasize the importance of weighing the harms of mammograms against the benefits in making informed decisions. However, little is known from national samples about how women perceive the harms and benefits of mammograms, and how these pe...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
This study was performed to systematically estimate the prognostic role of GAPLINC expression in cancer patients.MethodsSeveral electronic databases, including PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), and Wan Fang databases were searched for potential literature (updated to September 3, 2018). The pooled hazard ratios (HRs), odds ratios (ORs) and 95% confidence intervals (CIs) were calculated with a fixed effects model using Stata12.0 software.ResultsThe pooled results indicated that elevated GAPLINC was significantly related to shorter overall survival (OS) (HR = 1.66, 95% CI: 1.40-1.93, p
Source: Pathology Research and Practice - Category: Pathology Source Type: research
The overall number of T1 melanomas undergoing nodal biopsy have decreased following the 7th edition of the AJCC Cancer Staging Manual (AJCC 7), according to a new study.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: Hematology-Oncology News Source Type: news
Publication date: Available online 16 March 2019Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Isabela de Cássia Marins Quinsan, Gustavo Carvalho Costa, Antonio Vitor Martins Priante, Cesar Augusto Cardoso, Caio Luis S. NunesAbstractIntroductionCancer of the oral cavity and oropharynx exhibits an aggressive behavior and its diagnosis is, in most cases, attained at advanced stages. Total glossectomy is a therapeutic option in locally advanced cancer, and the only choice in the presence of recurrent or residual disease after chemoradiotherapy.ObjectiveTo evaluate the clinical-epidemiological profile, posto...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
The objective of the review to demonstrate the causal association between trans fatty acid intake and increase the risk of coronary heart disease through their influence on lipoprotein, association with atherosclerosis, stroke, diabetes and cancer.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 16 March 2019Source: International Journal of PharmaceuticsAuthor(s): Jian Liu, Qilong Wang, Michael Adu-Frimpong, Qiuyu Wei, Yujiao Xie, Kangyi Zhang, Chunmei Wei, Wen Weng, Hao Ji, Elmurat Toreniyazov, Ximing Xu, Jiangnan YuAbstractIsoliquiritigenin (ISL) has a great variety of pharmacological effects especially liver cancer therapy, but its poor solubility, bioavailability and liver targeting have limited its clinical use. In order to solve the aforementioned shortcomings, the TPGS-modified proliposomes loaded with ISL (ISL-TPGS-PLP) was prepared in this study. ISL-TPGS-PLP was fabrica...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: May 2019Source: Biomedicine &Pharmacotherapy, Volume 113Author(s): Yadong Wang, Shaorui Liu, Wei Dong, Xiao Qu, Cuicui Huang, Tao Yan, Jiajun DuAbstractLung cancer remains the leading cause of oncological death. There is an urgent need to discover new molecular targets and to develop new treatments. One of the UDP-glucuronosyltransferases (UGTs) family, UGT1A3, is highly expressed in lung adenocarcinoma (LUAD), and is associated with poor prognosis. Its inhibitor, hesperetin, may play an important role in anticancer therapy. The purpose of this study was to investigate the role of UGT1A3 in the progre...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: May 2019Source: Biomedicine &Pharmacotherapy, Volume 113Author(s): Zhenzhen Guo, Linlin Sui, Jia Qi, Qiannan Sun, Yuefei Xu, Na Zou, Yunpeng Xie, Ying KongAbstractMicroRNAs (miRNAs) are a class of small non-coding RNAs that are closely associated with carcinogenesis. Accumulating data indicate that miR-196b participates in the development of various types of cancers. However, the role of miR-196b in the formation of hydatidiform mole (HM) is still unclear. Our previous studies have demonstrated that miR-196b levels were decreased in JAR and BeWo cells and in HM tissue samples, as demonstrated by RT-PC...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In conclusion, IDH1R132C mutation was relatively prevalent in ICC. P2RX7 might be a potential downstream gene and it might be related to exosomes releasement.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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