Complete remission of nephrotic syndrome secondary to amyloid a amyloidosis in patient with inactive Crohn's disease after treatment by infliximab.
We present a case of a 34-year-old female patient with CD treated by azathioprine with inactive disease for three years and who developed a nephrotic syndrome secondary to AA amyloidosis. The treatment by infliximab for one year leads to a complete remission of the nephrotic syndrome. In this case, this complication occurred while the patient was clinically well, with biological and endoscopic markers showing an inactive or only mildly active disease. Infliximab could be a useful tool for a successful treatment of amyloidosis secondary to CD. PMID: 29657220 [PubMed - in process]
Conclusions: Between 2007 and 2010, endoscopic monitoring of patients within the first year after CD-related surgery was less than adequate based on current standards, but showed improvement. Medication changes were in general agreement with current guideline recommendations. This work was presented as a poster (number P686) by M. Barreiro-de Acosta et al. at ECCO (European Crohn's and Colitis Organisation) '18 in Vienna, Austria, 14-17 February 2018. PMID: 31203691 [PubMed - as supplied by publisher]
Conclusions: IBD causes a significant burden to the Finnish healthcare system. This study provides a detailed characterization of the cost landscape of IBD and contributes to optimizing treatment strategies and healthcare resource use in the biosimilar era. PMID: 31203693 [PubMed - as supplied by publisher]
Conclusion: Vascular abnormalities of the liver were commonly observed in thioguanine treated IBD patients, although these were not progressive and remained of limited clinical relevance over time. PMID: 31203688 [PubMed - as supplied by publisher]
The evidence for cardiovascular risk stratification in kidney transplant recipients is lacking in this population. Might more field-specific research help bridge the gap?Nephrology Dialysis Transplantation
In what ways has the use of increased risk donors impacted the outcomes of pediatric kidney transplants?American Journal of Transplantation
Publication date: Available online 17 June 2019Source: International Journal of Pediatrics and Adolescent MedicineAuthor(s): Kahlid Alshaigi, Reema Albraheem, Khalid Alsaleem, Moneer Zakaria, Aman Jobeir, Hesham AldhalaanAbstractBackgroundThe autism spectrum disorder (ASD) diagnosed children have social and cognitive disabilities. For parents, these behaviors can lead to humiliation, social exclusion and isolation. Stigma is a problem that not only may affect the individual with high functioning autism, but has the potential to extend to their family as well. Indeed, research indicates that the parents of children with dis...
ConclusionsDGBX significantly alleviates abnormal tumor-induced EPC accumulation, inhibits B16 melanoma progression, and enhances anti-tumor immune responses.Graphical abstract
This study aimed to analyze the primary stability of dental implant in maxillary and mandibular anterior and posterior regions using a finite element analysis.Materials and methodsCBCT images of maxillary and mandibular regions were collected from patients’ radiographic data and transformed to 3D models. A Straumann Dental implant was inserted in each bone model and then pulled-out, where amount von-Mises stress was obtained and analyzed for each. A comparison between the insertion and the pull-out was evaluated.ResultsTwenty-four images were randomly selected for analysis from 122 scans. In both the insertion and th...
Publication date: Available online 18 June 2019Source: Journal of the Saudi Heart AssociationAuthor(s): Jakrin Kewcharoen, Narut Prasitlumkum, Chanavuth Kanitsoraphan, Nattawat Charoenpoonsiri, Natthapon Angsubhakorn, Prapaipan Putthapiban, Pattara Rattanawong
Publication date: Available online 31 May 2019Source: Journal of the Saudi Heart AssociationAuthor(s): Leia Hee, Oliver J. Gibbs, Joseph G. Assad, Lokesh D. Sharma, Andrew Hopkins, Craig P. Juergens, Sidney Lo, Christian J. MussapAbstractObjectivesThe primary aim was to investigate the efficacy and safety of dual antiplatelet therapy (DAPT) using ticagrelor (T-DAPT) versus clopidogrel (C-DAPT) in a real-world ST-elevation myocardial infarction (STEMI) population.MethodsWe retrospectively analyzed 655 consecutive patients having primary percutaneous coronary intervention (PCI) for STEMI at Liverpool Hospital, Sydney, Austra...