Oropharyngeal Dysphagia Evaluation Tools in Adults with Solid Malignancies Outside the Head and Neck and Upper GI Tract: A Systematic Review

AbstractDysphagia is often associated with head and neck and upper gastrointestinal (GI) tract cancers. Evidence suggests that those with solid malignancies in other primary sites may also have swallowing difficulties. Timely and accurate identification of dysphagia is important given the impact it has on hydration, medical treatment, nutrition, prognosis, and quality of life. A systematic review was conducted to identify swallow screening, evaluation, and quality of life tools for those with solid malignancies outside the head and neck and upper GI tract. Ten electronic databases, one journal and two published conference proceedings were searched. Following deduplication, 7435 studies were examined for relevance. No tools were validated solely in this cancer population, though some included this group in larger cohorts. Comments are provided on the diagnostic properties and applicability of these tools. In the absence of appropriate diagnostic instruments, the exact prevalence of dysphagia and its impact on clinical and psychosocial well-being remain unknown. Accurate and adequate measurement of therapeutic intervention is also compromised. This review establishes the need for validated dysphagia evaluation tools for this clinical population.
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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AbstractPurpose of ReviewThe treatment paradigm for oral cavity and oropharyngeal cancer is shifting. As our treatment strategies change, it calls into question whether surveillance strategies warrant change as well. Therefore, the goal of this paper is to critically review the literature with respect to the current pattern and timing of surveillance and the use of post-treatment imaging in patients with oral cavity and oropharyngeal carcinoma.Recent FindingsRecent studies suggest that routine surveillance does not improve overall survival, but it does improve locoregional control. Imaging does play an important role in po...
Source: Current Otorhinolaryngology Reports - Category: ENT & OMF Source Type: research
ConclusionOur data can estimate abundance of OPC in male and female head and neck cancer patients and is helpful to use effective strategies for antifungal treatment, prophylaxis, and preventive therapies in these patients.
Source: Journal of Medical Mycology - Category: Biology Source Type: research
ConclusionFor the assessment of HNSCC recurrence after (chemo)radiation by DW-MRI, moderate interobserver agreement and substantial intraobserver agreement was found.
Source: European Journal of Radiology - Category: Radiology Source Type: research
ConclusionRéunion Island features some particularities in terms of incidence: women are less than half as likely as in Metropolitan France to develop any type of cancer, whereas incidence in males is among highest in France. The presentation of results in cancer registries could be improved in line with everyday practice in head and neck surgery.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
Publication date: Available online 31 January 2018Source: Seminars in Cancer BiologyAuthor(s): Benjamin Solomon, Richard J. Young, Danny RischinAbstractHead and neck squamous cell carcinoma (HNSCC) comprises a heterogeneous group of tumors that arise from the squamous epithelium of the oral cavity, oropharynx, larynx and hypopharynx. While many HNSCCs are related to classical etiologic factors of smoking and alcohol, a clinically, genomically, and immunologically distinct subgroup of tumors arise from the epithelium of the tonsil and the base of tongue as a result of infection with Human Papilloma Virus (HPV). In this revi...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
AbstractBackground and purposeA  prospective instrumental assessment of late dysphagia using swallowing organs at risk (SWOARs)-sparing IMRT for nasopharyngeal and oropharyngeal cancers.Materials and methodsObjective instrumental assessment included fiberoptic endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VFS) at baseline, and at 6 and 12  months after treatment. FEES assessed the pharyngeal residue according to the Farneti pooling score (P-score) as follows: 4–5 no dysphagia; 6–7 mild dysphagia; 8–9 moderate dysphagia; 10–11 severe dysphagia. Three different c...
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research
Opinion statementA larger proportion of patients with head and neck cancers (HNC) are now surviving, constituting up to 3% of all cancer survivors. This is likely due in part to the increase in HPV-related oropharyngeal cancers affecting younger individuals and with a better prognosis and to the improved outcomes of other HNCs as well over the last two decades. Most studies have previously been focusing on improving risk stratification, treatment and disease-related outcomes. Over the last decade, there has been an evolving interest in the field of survivorship care. Despite the collaborative efforts from a multidisciplina...
Source: Current Treatment Options in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionOur data can estimate abundance of OPC in male and female head and neck cancer patients and is helpful to use effective strategies for antifungal treatment, prophylaxis, and preventive therapies in these patients.
Source: Journal of Medical Mycology - Category: Biology Source Type: research
ConclusionThe trial demonstrates the clinical relevance of CAP in cancer treatment. There are three approaches for discussion of tumor remission: (i) the role of myeloid cells, (ii) the ROS/RNS model of cellular impact and (iii) the immunogenic cell death model of cancer treatment, and there is a reflection on non-sustainable tumor response due to adapted tumor microenvironment.
Source: Clinical Plasma Medicine - Category: Research Source Type: research
ConclusionFor the assessment of HNSCC recurrence after (chemo)radiation by DW-MRI, moderate interobserver agreement and substantial intraobserver agreement was found.
Source: European Journal of Radiology - Category: Radiology Source Type: research
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