Transplanting Thoracic Organs from Hepatitis C Positive Donors to Hepatitis C Uninfected Recipients

Given the need for thoracic organs and the high mortality of patients awaiting heart or lung transplantation, it is imperative to find ways to increase the donor pool. An approach that can immediately and substantially increase organ availability is to safely utilize thoracic organs from donors infected with hepatitis C virus (HCV). With the advent of direct acting antivirals (DAA) and recent advances in HCV treatment, we designed and implemented a clinical trial to assess the safety and efficacy of transplanting thoracic organs from HCV positive donors into HCV uninfected recipients.

Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: A.E. Woolley, S.K. Singh, H.R. Mallidi, M.M. Givertz, H.J. Goldberg, M.R. Mehra, L.L. Coakley, A.E. Kusztos, K. Chen, J. Fanikos, F.M. Marty, D. Harrington, P.C. Camp, L.R. Baden Source Type: research