Treat gestational diabetes with insulin and/or oral antidiabetic agents when lifestyle changes are not effective

AbstractTreatment of gestational diabetes is important to achieve glycaemic control and reduce the risk of fetal and maternal complications. If nutritional therapy and/or physical activity are ineffective, treatment with insulin is usually recommended. Although metformin and glyburide (glibenclamide) are effective oral antidiabetics, their benefits and risks in treatment gestational diabetes should be carefully considered, as both agents cross the placenta and data on their long-term safety in pregnant women and fetuses are lacking.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research