Transforming growth factor- β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion

Conclusions TGF-β modulates CAFs', but not FBs', cell shape, stiffness and invasion. General Significance Our findings elucidate on the effects of TGF-β on CAFs' behavior and stiffness providing new insights into the mechanisms involved. Graphical abstract
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research