Elevated MIC values to imidazole drugs among Aspergillus fumigatus isolates with TR34/L98H/S297T/F495I mutation.

In conclusion, this study suggested that environmental use of imidazole fungicides might confer selection pressure for the emergence of azole resistance in A. fumigatus.
PMID: 29507067 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - March 5, 2018 Category: Microbiology Authors: Chen Y, Li Z, Han X, Tian S, Zhao J, Chen F, Su X, Zhao J, Zou Z, Gong Y, Qu F, Qiu G, Wang S, Jia X, Lu Z, Hu M, Huang L, Verweij PE, Han L Tags: Antimicrob Agents Chemother Source Type: research