Sudden unexplained death in the young: epidemiology, aetiology and value of the clinically guided genetic screening

ConclusionSudden death in the young is of cardiovascular origin in the majority of cases. A considerable rate of SD cases remains of unknown cause on post-mortem. Apart from channelopathies, subclinical forms of inherited structural heart diseases would appear to be implicated in SADS. Clinically guided genetic screening has a significant diagnostic yield and identifies affected families that would have been missed by the current suggested molecular autopsy panel.
Source: Europace - Category: Cardiology Source Type: research