Endoscopic resection with adjuvant chemo-radiotherapy for superficial esophageal squamous cell carcinoma: a critical review

Radical esophagectomy with extended lymph node dissection is considered the standard of care in treatment of squamous cell carcinoma of esophagus with deep mucosal invasion (pT1a m3) or submucosal involvement (pT1b). However, despite the increasing use of minimally invasive approaches, it remains a major surgery associated with significant morbidities and even mortality risk. Endoscopic resection (ER) results in excellent local control in early superficial mucosal (pT1a) disease yet there is substantial risk of lymph node metastases in T1b disease.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research