Creatine kinase level and its relationship with quantitative electromyographic characteristics in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that involves both upper and lower motor neurons and eventually leads to muscle weakness, muscle atrophy, bulbar palsy, and respiratory failure. Creatine kinase (CK) is an enzyme that catalyzes the reversible conversion of creatine and utilizes adenosine triphosphate (ATP) to generate phosphocreatine and adenosine diphosphate. This enzyme is important in tissues and cells that rapidly consume ATP, particularly skeletal muscle.

Source: Clinical Neurophysiology - February 19, 2018 Category: Neuroscience Authors: Hongfei Tai, Liying Cui, Mingsheng Liu, Yuzhou Guan, Xiaoguang Li, Dongchao Shen, Kang Zhang, Shuangwu Liu, Shuang Wu, Qingyun Ding, Youfang Hu Source Type: research