Microbiome-Host Interactions in Hematopoietic Stem-Cell Transplant Recipients
• Microbiome alterations are associated with infection, GVHD, and other adverse transplant outcomes.• “Multi-omic” technologies may better identify clinically actionable microbiome biomarkers.• Functional microbial characterization may improve diagnostic and therapeutic strategies.• Know ledge gaps persist in chronic GVHD and extra-intestinal microbiome-host interactions.• Multi-institutional studies and data collection expansion will maximize microbiome research impact.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tessa Andermann, Jonathan Peled, Christine Ho, Pavan Reddy, Marcie Riches, Rainer Storb, Takanori Teshima, Marcel van den Brink, Amin Alousi, Sophia Balderman, Patrizia Chiusolo, William Clark, Ernst Holler, Alan Howard, Leslie Kean, Andrew Koh, Philip Mc Source Type: research