Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices

We present a consensus report pertaining to the improved clarity of definitions and classification of glomerular lesions in lupus nephritis that derived from a meeting of 18 members of an international nephropathology working group in Leiden, Netherlands, in 2016. Here we report detailed recommendations on issues for which we can propose adjustments based on existing evidence and current consensus opinion (phase 1). New definitions are provided for mesangial hypercellularity and for cellular, fibrocellular, and fibrous crescents.

Source: Kidney International - February 16, 2018 Category: Urology & Nephrology Authors: Ingeborg M. Bajema, Suzanne Wilhelmus, Charles E. Alpers, Jan A. Bruijn, Robert B. Colvin, H. Terence Cook, Vivette D. D ’Agati, Franco Ferrario, Mark Haas, J. Charles Jennette, Kensuke Joh, Cynthia C. Nast, Laure-Hélène Noël, Emilie C. Rijnink, Ian Tags: Meeting Report Source Type: research