Science self-corrects: Cancer gene does not pass reproducibility test

(Cold Spring Harbor Laboratory) About 10 years ago, several labs discovered that a gene called MELK is overexpressed, or turned on to a high degree, in many cancer cell types. This evidence has prompted multiple ongoing clinical trials to test whether drugs that inhibit MELK can treat cancer in patients. Now, CSHL researchers report that MELK is not actually involved in cancer. It's a story about how science self-corrects.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news