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New discovery offers hope of protecting premature babies from blindness

(University of Gothenburg) Now there is hope of a new way to protect extremely premature babies from impaired vision or blindness resulting from the eye disease retinopathy of prematurity (ROP). A study at Sahlgrenska Academy published in JAMA Ophthalmology points to a clear link between ROP and low levels of the fatty acid arachidonic acid, measured in children's blood.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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CONCLUSION: Early diagnosis and strict control of inflammatory activity have led to a dramatic reduction in the incidence of vision-threatening secondary complications. In the majority of cases, it has also been possible to resolve cystoid macular edema, which, if insufficiently controlled by systemic therapy, usually responds well to intravitreal dexamethasone implants. PMID: 29452454 [PubMed - as supplied by publisher]
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
ConclusionsThere is a positive association between maternal TSH in the ​​first trimester of pregnancy and the incidence of perinatal loss and miscarriage. The TSH cut‐off value of 2.5 mIU/L identified women with higher adverse pregnancy outcomes.This article is protected by copyright. All rights reserved.
Source: Clinical Endocrinology - Category: Endocrinology Authors: Tags: Original Article Source Type: research
Authors: Promelle V, Milazzo S Abstract Retinopathy of prematurity is a retinal vasoproliferative disease affecting extremely preterm infants exposed to high concentrations of oxygen therapy. Infants born before 32 post-menstrual weeks or with a birth weight of less than 1500g should systematically have a dilated fundus examination. The time of screening and schedule for follow-up are guided by the various risk factors. This disease results from immaturity of the peripheral retinal vessels at the time of premature birth. The classification of ROP depends on the anteroposterior extent of involvement (from cente...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
CONCLUSION: IVB is a safe and effective first-line treatment for ROP and should be considered in resource-limited centres. PMID: 28281426 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
With increased survival of very premature infants in the United States and across the world, retinopathy of prematurity (ROP) remains a leading cause of preventable childhood visual impairment and blindness. Premature birth requires that retinal maturation take place in a physiologically abnormal environment, leading to retinal injury and dysregulated growth and development. Although the pathophysiology of ROP is understood to involve exposure to extrauterine hypoxia and hyperoxia, multiple international studies have failed to identify the optimal approach to preventing ROP. Clinical efforts therefore center on optimizing ...
Source: NeoReviews recent issues - Category: Pediatrics Authors: Tags: Pediatric Drug Labeling Update Articles Source Type: news
Childhood glaucomaEye movement disordersEye cancerOptic nerve disorders We use the latest advances in pediatric ophthalmology to optimize your child ’s vision and eye health.Diagnosis and treatment of pediatric eye diseasesPrompt identification of childhood eye and vision problems is often the best way to preserve or regain vision.   This applies to common pediatric eye conditions such as refractive error requiring eyeglasses, amblyopia (or lazy eye) and strabismus (eyes that are not straight), as well as serious eye conditions such as childhood cataract, glaucoma, retinopathy of prematurity, and an eye tumor c...
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news
Aims To discern treatable and preventable causes of childhood blindness by evaluating the aetiologic factors, and to compare the distribution of the most commonly affected anatomic sites of severe visual impairment (SVI) with our previous published data. Methods The charts of 11 871 patients followed between June 2002 and May 2014 were reviewed retrospectively, and 695 patients (5.9%) who had SVI or blindness in accordance with WHO criteria were enrolled. The results of ophthalmologic examinations and coexistence of any systemic disease were documented and checked against our published clinic data concerning the aeti...
Source: British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Lens and zonules, Retina, Vision, Neurology Original articles - Clinical science Source Type: research
A unique tele-imaging screening model that originated in Karnataka and has been taken to other states offers hope to premature babies at a risk of lifetime blindness.
Source: The Economic Times Healthcare and Biotech News - Category: Pharmaceuticals Source Type: news
Abstract AIMS: To discern treatable and preventable causes of childhood blindness by evaluating the aetiologic factors, and to compare the distribution of the most commonly affected anatomic sites of severe visual impairment (SVI) with our previous published data. METHODS: The charts of 11 871 patients followed between June 2002 and May 2014 were reviewed retrospectively, and 695 patients (5.9%) who had SVI or blindness in accordance with WHO criteria were enrolled. The results of ophthalmologic examinations and coexistence of any systemic disease were documented and checked against our published clinic dat...
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
Babymaking is easy when everything goes right. All it takes is a single—decidedly agreeable—act and the rest runs on autopilot for the next nine months. But it’s the “everything goes right” part that is the rub, because in too many cases, at least one thing goes wrong. In the U.S., about 18,000 times per year, that one thing is prematurity. The outlook has gotten better for premature babies over the last half century. In 1960, the survival rate for a 3.3 lb (1,500 gm) premie was just 28%. By 2010 it was 78%. But everything depends on the calendar: Babies born at, say, 27 weeks—out of the...
Source: TIME: Top Science and Health Stories - Category: Science Authors: Tags: Uncategorized neonatal intensive care unit NICU Pediatrics Preemies Premature Babies Source Type: news
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