Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SKCa, IKCa, and Kir2.1 channels

Conclusions: Reduced expression and function of SKCa, IKCa and Kir2.1 channels is associated with elevated blood pressure in rats fed a long-term high fat/high fructose diet. Rats fed a 28-week high fat/high fructose diet provide a relevant model of diet-induced hypertension.

Source: Clinical Science - February 7, 2018 Category: Biomedical Science Authors: Gradel, A. K. J., Salomonsson, M., Sorensen, C. M., Holstein-Rathlou, N.-H., Jensen, L. J. Tags: PublishAheadOfPrint Source Type: research