Granulomatosis with polyangiitis presenting as facial nerve palsy in a teenager

Granulomatosis with polyangiitis (GPA, previously known as Wegener's granulomatosis) is an autoimmune systemic small-vessel vasculitis, associated with the presence of anti-neurophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA). It is characterized by necrotizing granulomas, usually affecting the airways and kidneys. GPA should be considered when patients do not improve despite adequate treatment of otologic symptoms, when patients have unspecific symptoms suggesting systemic disease (e.g.

Source: International Journal of Pediatric Otorhinolaryngology - February 7, 2018 Category: ENT & OMF Authors: James C. Wang, Brittany A. Leader, Ryan A. Crane, Bernadette L. Koch, Matthew M. Smith, Stacey L. Ishman Tags: Case Report Source Type: research