Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman.

Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman.
Neurocase. 2018 Feb 01;:1-5
Authors: Tronnier VM, Rasche D, Thorns V, Alvarez-Fischer D, Münte TF, Zurowski B
Abstract
Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.
PMID: 29388475 [PubMed - as supplied by publisher]

Source: Neurocase - February 1, 2018 Category: Neurology Authors: Tronnier VM, Rasche D, Thorns V, Alvarez-Fischer D, Münte TF, Zurowski B Tags: Neurocase Source Type: research