Relationship between CNS and immunology, in relation to psychology.

Relationship between CNS and immunology, in relation to psychology. Curr Drug Metab. 2018 Jan 29;: Authors: Ashraf GM, Azhar A, Ali A, Rehan M, Zia Q, Owais M, Alexiou A, Rauf A, Ganash M, Kamal MA Abstract Higher animals, especially the human beings have the privilege of employing advanced central nervous system (CNS) as well as the evolved immune system to ward off various onslaughts throughout their life. Alterations in inflammatory and neural regulatory pathways lead to several disorders that are now becoming the cause of concern across the world. Deregulation in bidirectional network, particularly in aging population, leads to several neurodegenerative diseases such as having dementia as a one of the major characteristics. Interestingly, research updates have signified the role of abrupt immune regulation in several brain diseases, establishing a link between altered immune system and CNS related diseases. In the later period of life time, the role has altered the immune response in the pathogenesis of major psychiatric disorders, which has become more visible. Recent research advances have indicated a close relationship between emotion and psychology to diseases and immunology, proclaiming the need of providing enhanced attention on mechanistic aspect of psychoneuroimmunological disorders. In the present manuscript, we present a synopsis on the linkage of CNS and immune system with respect to psychology, with the aim to further...
Source: Current Drug Metabolism - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Metab Source Type: research