Bone marrow mesenchymal stem cells promote head and neck cancer progression through Periostin ‐mediated phosphoinositide 3‐kinase/Akt/mammalian target of rapamycin

In conclusion, this study indicated that BMMSC promoted proliferation, invasion, survival, tumorigenicity and migration of head and neck cancer through POSTN‐mediated PI3K/Akt/mTOR activation.

Bone marrow mesenchymal stem cells promoted proliferation, invasion, survival, tumorigenicity and migration of head and neck cancer through Periostin‐mediated PI3K/Akt/mTOR activation.

Source: Cancer Science - January 23, 2018 Category: Cancer & Oncology Authors: Chuanxia Liu, Xiaoxia Feng, Baixiang Wang, Xinhua Wang, Chaowei Wang, Mengfei Yu, Guifen Cao, Huiming Wang Tags: ORIGINAL ARTICLE Source Type: research