Predicting drug efficacy in chronic low back pain by quantitative sensory tests

ConclusionsThermal QST have the potential to predict imipramine effect in chronic low back pain. Oxycodone and clobazam effects could not be predicted by any of the selected QST or genetic variants.
SignificancePredicting drug efficacy in chronic low back pain remains difficult. There is some evidence that patients more sensitive to heat and cold pain respond better to imipramine.

Source: European Journal of Pain - January 23, 2018 Category: Anesthesiology Authors: J. Schliessbach, A. Siegenthaler, L. B ütikofer, P. Vuilleumier, P. Jüni, U. Stamer, L. Arendt‐Nielsen, M. Curatolo Tags: Original Article Source Type: research