Motor cortex synchronization influences the rhythm of motor performance in premanifest huntington's disease

Conclusions: Our data may model the ability of the motor command to respond to more subtle, physiological inputs from other brain areas. This novel insight indicates that impairments of the timing accuracy of synchronization and desynchronization could be a physiological basis for some key clinical features of Huntington's disease. © 2018 International Parkinson and Movement Disorder Society

Source: Movement Disorders - January 22, 2018 Category: Neurology Authors: Elias P. Casula, Isabella M. S. Mayer, Mahalekshmi Desikan, Sarah J. Tabrizi, John C. Rothwell, Michael Orth Tags: Research Article Source Type: research