Hepatitis B virus infection in the Democratic Republic of Congo: a systematic review of prevalence studies (2000 –2016)

ConclusionThis review suggests that DRC is a country characterized by an intermediate level of HBV infection endemicity rate. It remains however an important public health problem and efforts should continue in prevention and in policy to control this viral disease.
Source: Journal of Public Health - Category: Health Management Source Type: research

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Infectious hepatitis in pregnancy is clinically significant in both the acute and chronic phases. Here, we review the perinatal implications of chronic hepatitis B and C and acute hepatitis A and E. Familiarity with screening, transmission, diagnosis, and management of infectious hepatitis is of ongoing importance during obstetric care, as these diseases are endemic in much of the world. Pregnancy and interpregnancy care provide opportunities to prevent infection and transmission of hepatitis.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Liver Disease in Pregnancy Source Type: research
AbstractChina has the world's largest burden of hepatitis B virus (HBV) infection, but the country has made considerable progress in preventing its mother-to-child transmission (MTCT) in the past three decades. This feat is made possible due to the high coverage of birth-dose hepatitis B vaccine (HepB,> 95%), hepatitis B surface antigen (HBsAg) screening for pregnant women (> 99%), and hepatitis B immunoglobulin plus HepB for newborns whose mothers are HBsAg positive (> 99%). Studies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have also been conducted. However, China still ...
Source: Frontiers of Medicine - Category: General Medicine Source Type: research
This study confirms that hepatitis E is the leading cause of acute jaundice, leads to hospitalizations in all regions in Bangladesh, occurs throughout the year, and is associated with considerable morbidity and mortal ity. Effective control measures should be taken to reduce the risk of HEV infections including improvements in water quality, sanitation and hygiene practices and the introduction of HEV vaccine to high-risk groups.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
ConclusionsHBV prevalence in Dolpo is significantly higher than in the rest of Nepal. Targeted interventions are recommended to address liver and sexual health education, including the introduction of birth dose HBV vaccinations, HBV screening and HBV vaccinations for pregnant women in Dolpo.
Source: Journal of Public Health - Category: Health Management Source Type: research
In countries where hepatitis B virus (HBV) is endemic, including Senegal, the World Health Organization recommends systematic HBV screening of pregnant women and vaccination at birth to prevent mother-to-child...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
Contemporary clinicians who provide obstetric care acknowledge screening of pregnant women for perinatally transmissible infectious diseases as a routine component of prenatal care, although this has not always been the case. For example, prenatal screening for hepatitis B virus (HBV) infection only began to be discussed after rigorous trials conducted in the 1970s and 1980s in high-endemic areas demonstrated that identification of chronically infected pregnant women followed by targeted neonatal immunoprophylaxis (hepatitis B immunoglobulin and the first dose of HBV vaccine) significantly lowered the risk of chronic infec...
Source: JAMA - Category: General Medicine Source Type: research
Conclusion: A significant proportion of pregnant women have anti-HBs while the seroprevalence of HCV is low among pregnant women in the city of Mwanza. Routine screening of HBV among pregnant women coupled with appropriate management should be emphasized in developing countries. Further studies to determine seroprevalence of HCV are recommended across the country. PMID: 31316835 [PubMed - in process]
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
In a recent issue of Digestive and Liver Disease, Lembo et al. [1] presented an interesting survey on hepatitis B and hepatitis C prevalence in pregnancy in Southern Italy. Regarding hepatitis B virus (HBV), analyzing a cohort of 7,558 pregnant women, a prevalence of 0.5% was reported. Hepatitis B surface Antigen (HBsAg) seroprevalence was significantly higher among the 569 foreigners compared to the 5,559 Italian women (3% vs. 0.2%, p  
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
Chronic hepatitis B is a global health problem affecting approximately 350 million to 400 million individuals worldwide, and mother to child transmission remains the major mode of transmission. Approximately 50% of chronically infected individuals acquire infection, either perinatally or early in childhood, predominantly in areas where hepatitis B virus (HBV) is endemic. Management of HBV in pregnancy presents a unique set of challenges. All infants born of hepatitis B surface antigen –positive mothers should receive postexposure immune prophylaxis with hepatitis B immunoglobulin and HBV vaccination within 24 ho...
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research
CONCLUSIONS: The study demonstrated that the rate of seroprotection in the current vaccination programme against HBV in DRC was lower than desirable but comparable to rates reported in some other African countries. Further studies are needed to assess this finding and to evaluate ways to optimise the seroprotection rate. PMID: 31131798 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
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