Quantifying iron deposition within the substantia nigra of Parkinson's disease by quantitative susceptibility mapping

Iron deposition within the substantia nigra (SN) has been postulated to play a vital role in Parkinson's disease (PD). The aim of this study was to explore the inherent link of PD patients between their substantia nigra iron accumulation and clinical status using quantitative susceptibility mapping (QSM) which is now considered to be the only quantitative imaging technique of brain iron deposition.

Source: Journal of the Neurological Sciences - January 12, 2018 Category: Neurology Authors: Hedi An, Xiaoyan Zeng, Tengfei Niu, Gaiying Li, Jie Yang, Lanlan Zheng, Wei Zhou, Hong Liu, Miaomiao Zhang, Dongya Huang, Jianqi Li Source Type: research