Advances in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a heterogeneous course and systemic involvement. It is the result of a complex pathogenic pathway that culminates in autoantibody formation. The interaction between environmental triggers and genetic susceptibility is key in this process. Genome-wide association study technology has allowed the recognition of>80 loci associated with SLE that lead to the formation of key proteins, each contributing a small increase to the risk.
Source: Medicine - Category: Internal Medicine Authors: Tags: Systemic lupus erythematosus Source Type: research