Cytotoxic and inflammatory effects of alendronate and zolendronate on human osteoblasts, gingival fibroblasts and osteosarcoma cells

The aim of this paper was to assess the effects of zoledronate (ZOL) andalendronate (FOS) on apoptotic behaviour and gene expression of pro- and inflammatory cytokines of three cell types (human osteoblasts, human gingival fibroblasts and human osteogenic sarcoma cell lines) during a period of 4 weeks.

Source: Journal of Cranio-Maxillofacial Surgery - January 10, 2018 Category: ENT & OMF Authors: Yahya A çil, Mia Leena Arndt, Aydin Gülses, Henning Wieker, Hendrik Naujokat, Mustafa Ayna, Jörg Wiltfang Source Type: research