Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer.

Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer. Adv Exp Med Biol. 2017;1026:331-370 Authors: Lao L, Fan S, Song E Abstract Tumor-associated macrophages (TAMs) are the most abundant inflammatory infiltrates in the tumor stroma. TAMs promote tumor growth by suppressing immunocompetent cells, including neovascularization and supporting cancer stem cells. In the chapter, we discuss recent efforts in reprogramming or inhibiting tumor-protecting properties of TAMs, and developing potential strategies to increase the efficacy of breast cancer treatment. PMID: 29282692 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research