Epidemiology and antibiogram profile of Vibrio cholerae isolates between 2004-2013 from Odisha, India.

Epidemiology and antibiogram profile of Vibrio cholerae isolates between 2004-2013 from Odisha, India. Jpn J Infect Dis. 2017 Dec 26;: Authors: Pal BB, Nayak SR, Khuntia HK Abstract Cholera is an acute diarrhoeal disease caused by Vibrio cholerae O1 and O139 serogroups which are known to cause epidemics of cholera in Odisha. The present study has been envisaged to document the antibiotic resistance pattern among clinical isolates of both serogroups of V.cholerae O1 and O139 isolated during 2004-2013. Nine hundred nine isolates of V.cholerae were included in this study which were identified by standard procedures. Antibiotic sensitivity test was performed by disc diffusion method. The seasonality of cholera in this region indicated that there was one peak observed in the rainy season only. The cholera cases started increasing from the month of July and declined from the month of October onwards. The adult age group of patients were worst affected among all age group of patients. The two different serogroups of V.cholerae O1 and O139 showed different percentage of resistance to all the antibiotics in each year. The serogroup O1 showed uniform high resistance to co-trimoxazole, furazolidone, nalidixic acid throughout the study. Chloramphenicol showed resistance only during 2009, whereas it was sensitive for rest of the years. The emergence of multiple drug resistant V.cholerae may significantly influence the control of future outbreaks ...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research