A pragmatic randomized controlled trial comparing pathway-based versus usual care in community-acquired acute kidney injury.

A pragmatic randomized controlled trial comparing pathway-based versus usual care in community-acquired acute kidney injury. Saudi J Kidney Dis Transpl. 2017 Nov-Dec;28(6):1282-1292 Authors: Almalki AH, Ismail SE, Qureshi MA, Abunijem Z, Balla ME, Karsou S, Qureshi RA, Ahmad A, AlSulami S, Khalil M, Hafez J, Thomson JEH, Siddiqui MA, Yusuf OB, Zahrani ZA, Gasim A, Mujtaba Quadri KH Abstract Clinical pathways have shown conflicting evidence in improvement of several patient-centered outcomes across different clinical settings. However, the effectiveness of clinical pathway in management of acute kidney injury (AKI) has not been reported. Therefore, we aimed to assess the length of hospital stay (LOS) and patient-centered outcomes in community acquired AKI and compared pathway care (PC) versus usual care (UC). The CHAMP-Path AKI Trial is a pragmatic, parallel, single-blind randomized controlled trial. Physicians were randomized to provide either UC or PC. Patients were randomized through a computer-generated sequence. Allocation was concealed. Patients presenting to the emergency department with AKI and hemodynamic stability, who were over 14 years with a serum creatinine greater than 1.5 times the baseline were eligible. Patients with chronic kidney disease stages 4 or 5, kidney transplantation recipients, those admitted with obstructive uropathy, suspected glomerular or interstitial disease, and pregnant women were excluded. Thirty-e...
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research