Minor ías raciales/étnicas seriamente afectadas por diabetes tipo 2: Esto es lo que podemos hacer

Para leer en inglés Probablemente usted sabe que la diabetes tipo 2 se ha convertido en un problema enorme en el área de salud en los Estados Unidos de Norteamérica (EUA) y en el resto del mundo. Las personas con diabetes tipo 2 no pueden utilizar la glucosa (azúcar) que se obtiene de los alimentos como fuente de energía de forma eficiente. En consecuencia, los niveles de azúcar en la sangre están por encima de lo normal. Con el tiempo, esto puede causar complicaciones serias e incluso fatales como enfermedad cardiovascular, enfermedad de los riñones y enfermedad vascular cerebral. La elevación persistente del azúcar puede causar también problemas que interfieren con la calidad de vida, incluyendo cambios en la visión, dolor en las piernas por afección de los nervios (neuropatía) así como infecciones que no se curan tan rápidamente. ¡Se estima que 415 millones de adultos en el mundo sufren de diabetes, y que para el año 2040 esta cifra aumentará a 642 millones! Es un problema enorme tanto por el número de personas afectadas, así como por las consecuencias de la enfermedad si no es controlada adecuadamente. De los 30.3 millones de adultos con diabetes en los EUA, ¡23.1 millones de ellos sabían que tenían la enfermedad y 7.2 millones no lo sabían!   Es aún más preocupante la gran cant...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Health Source Type: blogs

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LncRNA GAS5 suppresses ER stress‑induced apoptosis and inflammation by regulating SERCA2b in HG‑treated retinal epithelial cell. Mol Med Rep. 2020 May 20;: Authors: Jiang L, Wang C, Shen X Abstract Hyperglycemia impairs the retinal functions in patients with diabetic retinopathy (DR). Downregulation of long non‑coding RNA growth arrest‑specific transcript 5 (lncRNA GAS5) expression in diabetes affects glucose intake and insulin signaling. Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) mediates the regulation of endoplasmic reticulum (ER) stress and apoptosis in high glucose (HG)‑tr...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Cui Y, Li Y, Ning J, Mi Y, Wang X, Qiu Z, Li L, Gou X Abstract Mechanical allodynia, which develops in patients of diabetes mellitus as a neuropathic manifestation, remains without an effective treatment. The aim of the present study was to investigate the effects and potential mechanisms underlying resveratrol (RES) in a rat model of streptozocin (STZ)‑induced diabetic mechanical allodynia (DMA). The rat model of DMA was established by the administration of an intraperitoneal injection of STZ. From day 8 post‑STZ injection, rats were administered with an intragastric injection of various doses of RES ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review). Mol Med Rep. 2020 May 22;: Authors: Jiang S, Young JL, Wang K, Qian Y, Cai L Abstract Diabetes mellitus (DM) is a growing health concern in society. Type 1 and type 2 DM are the two main types of diabetes; both types are chronic diseases that affect glucose metabolism in the body and the impaired regulation of glucose and lipid metabolism promotes the development and progression of DM. During the physiological metabolism process, the liver serves a unique role in glucose and...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusions: 60% of patients with MDD and/or AAD had at least one additional NCCD, which significantly increased the economic and humanistic burden. These findings are important for payers and clinicians in making treatment decisions. These results underscore the need for development of multi-pronged interventions which aim to improve quality of life and reduce activity limitations among patients with mental health disorders and NCCDs. PMID: 32468879 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
Publication date: Available online 29 May 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Alessandro Mantovani, Christopher D. Byrne, Ming-Hua Zheng, Giovanni Targher
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: Available online 29 May 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Elisabetta Torlone, Camilla Festa, Gloria Formoso, Marina Scavini, Maria Angela Sculli, Elena Succurro, Laura Sciacca, Paolo Di Bartolo, Francesco Purrello, Annunziata Lapolla
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
TYPE 2 DIABETES results in blood sugar being out of whack. The ever-increasing glucose levels need to be under control. Here's the best natural supplement to make management easier.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: T2DM patients have cognitive deficits on several domains compared to healthy participants. Domain specific neuropsychological deficits in middle aged T2DM patients have a significant impact on HRQOL. PMID: 32468306 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
CONCLUSIONS: Better staff training focused on care bundles preventing infections, better medical training focused on less efforts for CVC insertion, and the use of Ultrasounds during the CVC insertion may be the main factors that can lead to lower CLABSI rates in obese patients. Further research relating CLABSI rates in ICU patients and obesity is needed. PMID: 32468303 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Contributors : Kameron B Rodrigues ; Matthew J Dufort ; Alba Llibre ; Vincent Bondet ; Cate Speake ; Kristin V Tarbell ; Darragh DuffySeries Type : Expression profiling by arrayOrganism : Homo sapiensTruCulture human whole blood ex vivo stimulation was performed on 17 healthy individuals and 17 post-onset type 1 diabetics, then gene expression was analyzed using Nanostring to characterize stimulated innate immune responses. Ex vivo whole blood stimulation revealed higher induced IFN-1 responses in type 1 diabetes as compared to healthy controls.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
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