Acute cardiometabolic responses facilitating a state of chronic hyperglycemia and renal impairment: the SABPA study

BackgroundAugmented α-adrenergic response patterns are associated with vascular risk in Africans. Therefore, the aims of this study were (a) to assess ethnic differences related to glucose and cardiovascular responses during acute laboratory stress, and (b) to assess whether these responses are associated with chronic hyperglycemia (HbA1c≥5.7%) and albumin : creatinine ratio (ACR). Materials and methodsAmbulatory blood pressure of 81 African and 100 Caucasian men was recorded. Beat-to-beat blood pressure was obtained during exposure to the Color Word Conflict (STROOP) and Cold Pressor Tests (CPT). Overnight 8 h fasting urine, basal and post-stress blood samples were collected for biochemical analyses. ResultsAugmented glucose responses (P
Source: Cardiovascular Endocrinology - Category: Cardiology Tags: Original articles Source Type: research