Endoscopic detection rate of sessile serrated lesions in Lynch syndrome patients is comparable to an age- and gender-matched control population: case-control study with expert pathology review

Carcinogenesis in Lynch syndrome involves fast progression of adenomas to colorectal cancer (CRC) due to microsatellite instability. The role of sessile serrated lesions (SSLs) and the serrated neoplasia pathway in these patients is unknown. The aim of this matched case-control study was to compare endoscopic detection rates and distribution of SSLs in Lynch syndrome patients to a matched control population.

Source: Gastrointestinal Endoscopy - December 9, 2017 Category: Gastroenterology Authors: Jasper L.A. Vleugels, Husna Sahin, Yark Hazewinkel, Lianne Koens, Jose G. van den Berg, Monique E. van Leerdam, Evelien Dekker Source Type: research